You may have experienced the transformative effects of Dermal Fillers for yourself – plumped lips, heightened cheekbones, revived tear troughs – but you may not be aware of the enhanced results polynucleotides can achieve. Dermal Fillers and treatments such as Nucleofill stimulate different cell receptors and, when combined, create an unparalleled naturally-youthful look. 

What Are Polynucleotides?

Polynucleotides are the latest breakthrough in regenerative aesthetics. Nucleotides are the building blocks that form our DNA and RNA. By injecting long chains of nucleotides into the skin, treatments like Nucleofill implement change at a cellular level, instructing the skin to repair and renew. The powerful biostimulator activates membrane receptors in fibroblast and adipocyte cells, which form the majority of your body’s connective tissue. By enhancing their metabolic rate, collagen is regenerated and the growth rate of fibroblasts is increased. This bolsters the skin’s strength and integrity in the most natural way possible, resulting in improved texture, reduced fine lines and a more radiant complexion. 

In addition to this, Nucleofill may help to prevent photodamaged skin. When your fibroblasts are exposed to ultraviolet B radiation, polynucleotides are stimulated to induce DNA repair. When injected into the body, they protect cells from UV damage before it occurs, reducing the need for internal repair. Nucleofill also activates the A2A receptor associated with tissue regeneration, known for its anti-inflammatory properties. This makes the injectable effective against symptoms of rosacea.   

How Does Nucleofill Work Alongside Dermal Fillers?

The most common Dermal Fillers are made from cross-linked hyaluronic acid (HA). The viscous gel restores lost volume in ageing skin and creates delicate contours that bring facial features into balance. When injected, the solution stimulates fibroblasts to produce type I collagen, resulting in a subtle lifting effect over time. Localised cellular function is increased, mediated by up-regulation of type II TGF-β receptors and connective tissue growth factor. The extended support for the dermal extracellular matrix increases epidermal thickness and reduces the appearance of sagging skin. 

To put it simply, Dermal Fillers and Nucleofill provide a much more comprehensive approach to ageing when used in combination. Fillers replenish lost volume and enhance overall facial symmetry, whereas the restorative properties of Nucleofill harness your body’s ability to repair. Together, signs of ageing are reversed and cells are given the power to prevent future damage, resulting in a vibrant and youthful complexion.  

What Areas Can Be Treated?

Polynucleotides and Dermal Fillers can be used all over the body, although they are most commonly used to treat the face and neck. 3 distinct Nucleofill products are used to target different areas: Nucleofill Eyes focuses on reducing fine lines and crepiness around the eye area; Nucleofill Skin repairs cell damage on the face and body; and Nucleofill Hair promotes hair growth where hair is thinning or lost altogether. 

How Do I Book My Treatment?

Polynucleotide treatments beautifully complement Dermal Fillers. To find out which areas of your face would benefit most from each treatment, book a consultation with one of the skilled practitioners at The Lovely Clinic. After examining your skin, they will use their expertise to create a treatment plan uniquely tailored to your skin concerns. Whether you wish to treat signs of ageing, asymmetry or photodamaged skin, we will combine the most suitable products and techniques to achieve your desired look.  

Call 020 3695 5400, email hello@thelovelyclinic.co.uk, or complete our online contact form to schedule your appointment.